Growing up in college towns, Mark has wanted to be an architect since he was in the seventh grade. At Princeton University, Mark competed in varsity track while earning his degree summa cum laude in Architecture. Mark continued on to Harvard University, where he completed his Masters in Architecture in 1992. While a student, he illustrated two books on the modernist Swiss bridge designer, Robert Maillart.

Interested in the convergence of science and architecture, Mark began his career at Payette Associates, later becoming a founding partner at Wilson Architects. At the age of 40, he joined Tsoi/Kobus & Associates as Principal/Vice President and leader of the Science and Technology practice.

Mark has published extensively on the architecture of science, in such publications as Tradeline, Labs for the 21st Century and Lab Design. He has conducted workshops and spoken at conferences throughout the country on topics related to laboratory design and sustainable design practices. He has also taught at the Boston Architectural College, and has served as a thesis advisor.

Mark is a LEED accredited and licensed architect.